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Opko invests in medical device company

Neovasc (Toronto: NVC) said Opko (AMEX: OPK) were part of a private placement of 4.72 million equity units priced at $1 each; $720,500 more was raised than initially planned.
The units consist of one common share and a warrant for a half a share, exercisable at $1.25 a share for two years.
Neovasc is thinly traded, and Yahoo last shows a trade at $1 Canadian on Aug. 11. The company has a 52-week range of 18 cents to $1.40 and a stock market capitalization of $40.77 million.
Neovasc said it is testing an implantable product for treating angina and another device to treat heart valve disease.
Another participant in the placement was Gagnon Securities LLC, of New York City, whose members invested $1.42 million.
"We are encouraged by the strong support we received from new investors in this oversubscribed financing," Neovasc CEO Alexei Marko news release. "Completion of this placement provides Neovasc with the necessary funding to significantly advance our pipeline projects that we believe have substantial clinical and commercial potential."
 

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The insider buying on OPK is in turbo drive right now.
Phillip Frost is buying shares by the hundreds of thousands this month at market prices.
This is not value buying. OPK is not anywhere close to any 52 weeks lows.

Insiders are very bullish here.

Im still fully on board after a brief vacation after the overall market implosion.

Was able to get back in almost at the same price I sold out.
 

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Stock is holding up pretty good despite the market getting hammered the last few trading days.
Frost is still buying, and his pace is picking up.
 

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I'm sure you've heard the saying "Talk is cheap," and the vast majority of the time people are just talking rather than putting money behind their words. However, I did a quick scan and found two enticing companies that have had some very nice insider buying along with some interesting growth prospects.

Dr. Phillip Frost is a billionaire who initially was a professor of dermatology at the University of Miami from 1966-1972 and chairman of the same department from 1972-1990. During that time, he forged a history of building up pharmaceutical companies and selling them at a great profit, most notably Key Pharmaceuticals which was acquired by Schering-Plough for $600 million in 1986 and Ivax Corp. sold to Teva Pharmaceuticals (TEVA) and who he currently serves as its chairman for $7.4 billion in 2006. His new target very clearly looks to be Opko Health (OPK), which he serves as both the chairman and chief executive officer. Opko is a multi-national pharmaceutical and diagnostics company focused on wide array of areas, most notably, Alzheimer's and Parkinson's disease, along with non-small cell lung cancer. These of course are very lucrative markets if any of their various products in Phase II and Phase III gain FDA approval. I personally tend to stay away from these riskier biotechnology/pharmaceutical stocks which don't have a steady stream of revenue or free cash flow, but this to me is more a management play than betting on the next big wonder drug. Moreover, other insiders as well are buying on the open market as well and that shows me that they have a lot of confidence in their drug pipeline.

Dr. Frost himself seems to have a religious conviction of buying at least 10,000 shares per trading day for the better part of two years and now owns over 105 million shares of the approximately 285 million weighted average number of shares outstanding, basic and diluted according to their most recent SEC 10-Q ending June 30, 2011. That is well over 33% of the firm owned by him and he seems to have the capital and strong will to continue gobbling more of it. OPK had a 27 million secondary offering on March 14, 2011 at $3.75 per share and was actually oversubscribed by 2.397 million shares showing strong support at that price. Moreover, on June 20, 2011, OPK repurchased 2.398 million shares from an early investor in Acuity Pharmaceuticals at a price of $3.25 per share. On a valuation basis, Opko can't really be measured, much like most other high growth companies, since their potential profits come from expected revenue streams yet to be realized and so little, if any, in terms of revenue, book value, and free cash flow are existent. Hence, I'll look more to the management once again as they have really proven to me that they are confident in the company and gladly snap up shares that others are giving away cheaply. I'm thinking of starting a position at $3.75 matching the secondary price and if by any chance it drops to $3.25, really look to back up the truck as the company itself is repurchasing shares at that level.

The heavy insider buying in Ladenburg Thalmann Financial Services (LTS) not only by Dr. Frost, but other insiders as well, is encouraging. Along with Dr. Frost's 100,000 share buy on August. 18, he followed that up with a 60,000 share buy on August 24 and 40,000 share buy on August 25. Moreover, many insiders have bought over the last two weeks more than 100,000 shares collectively, including CEO Richard Lampen. Putting aside the heavy insider buying, I find this as one of the very few financial services company based in Miami, which of course is still a premiere destination for retirees worldwide and as such, Ladenburg's financial advisory and asset management divisions will look to capitalize greatly as the baby boomers continue to retire. Just recently on August 17th, Ladenburg acquired Securities America from Ameriprise Financial and its $50 billion in assets under management, along with their 1,700 financial professionals for $150 million in cash and other considerations.

This more than tripled Ladenburg's size from $20 billion to now collectively $70 billion in assets under management, allowing them now to benefit from scales of economy and doing it at a price that was less than one-third the cost if Ladenburg were to acquire its own shares (Ladenburg essentially paid 30x for the assets under management of Securities America, whereas at the time of the announcement, Ladenburg was trading at 110x its own assets under management). I think this company is worth buying at $1.20 per share when it's trading at approximately 1x Price/sales and at $1 per share has been showing very strong insider support and worth increasing one's holdings considerably.
 

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Doing well.
At one point today 4.60
Closed at a new thread high.
Huge volume including Mr Frost and other insiders.
I see 5.00 in the near future
 

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Pretty big news. OPK leaving the AMEX and moving up to the NYSE
We are moving up to the big board folks.
This should attract a whole new range of investors.
 

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http://www.bizjournals.com/southflorida/news/2011/09/14/opko-moving-to-nyse.html?ana=yfcpc


Dr. Phillip Frost is moving Opko Health up to the New York Stock Exchange.
The Miami-based biotechnology and pharmaceutical sales company (OPK) currently trades on the Amex. Opko Health announced that it should start trading on the NYSE on Friday.
Frost, a Miami Beach billionaire and Opko Health’s chairman and CEO, has plenty of experience leading companies on a major exchange. He founded and led Miami-based Ivax Corp., which was bought by Teva Pharmaceuticals, where he is now chairman.
Frost is also a large investor in Miami-based Ladenburg Thalmann Corp . (AMEX: LTS), Miami-based Vector Group (NYSE: VGR) and Miami-based Safestitch Medical (OTCBB: SFES).
“Unparalleled access to the global investment community and improved liquidity are important benefits of listing on the NYSE,” Frost stated in a news release. “The move reflects our interest in providing our current and future investor base the most efficient market for trading Opko’s shares.”
Frost owns over 106 million shares of Opko.
Opko Health lost $11.45 million on revenue of $18.8 million in the first six months of 2011. Much of its operations are focused on developing biotechnology.
Shares of Opko Health traded down 7 cents to $4.41 early Wednesday. The 52-week high was $5.03 on Feb. 16. The 52-week low was $2.02 on Sept. 14, 2010.
 

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MIAMI--(BUSINESS WIRE)-- OPKO Health, Inc. (NYSE Amex: OPK) (“OPKO,” “OPKO Health” or the “Company”) today announced that it has received authorization to transfer the listing of its Common Stock from the NYSE Amex to the New York Stock Exchange (“NYSE”). The Company’s Common Stock will continue to trade under the ticker symbol “OPK.” The Company’s Common Stock is expected to begin trading on the NYSE on or about September 16, 2011.

Phillip Frost, M.D., the Company’s Chairman and CEO commented, “Unparalleled access to the global investment community and improved liquidity are important benefits of listing on the NYSE. The move reflects our interest in providing our current and future investor base the most efficient market for trading OPKO’s shares. I would like to thank the NYSE Amex team for their support in managing our listing to this point.”

“As having been part of our community of listed companies with its NYSE Amex listing, we are privileged to welcome OPKO Health to the New York Stock Exchange,” said Duncan L. Niederauer, CEO, NYSE Euronext. “We value OPKO Health’s ongoing partnership and reaffirm our commitment to the company and its shareholders to provide the highest levels of market quality, liquidity and service.”

The Company has notified the NYSE Amex that it will voluntarily delist its Common Stock from the NYSE Amex. The last day of trading of the Common Stock on the NYSE Amex is expected to be on or about September 15, 2011. Until the Company’s Common Stock begins trading on the NYSE, the Company’s Common Stock will remain trading on the NYSE Amex under the ticker symbol “OPK.”
 

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chop what exactly does this mean as far as the potential for the stock??

There are a lot of mutual funds that will not invest in the AMEX exchange.
Some mutual funds have a NYSE/NASDAQ only rule.
So for all the funds that had that rule OPK was off limits.

Thats why this will attract a whole new group of investors.

OPK only has about 15% of its shares bought from mutual funds.
There is potential for a big bump from these new funds that did not have the ability to buy OPK in the past.

$5.00 a share is also another key number.
Most MF are not allowed to buy any companies below 5 a share.

So if we can hit 5 and be on the NYSE that could be double great.
 

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And also just being on the NYSE gives you a certain cred that being on the AMEX does not give you
 

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Tomorrow will be interesting.
1st day on the NYSE
 

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This story im about to link below has nothing to do with OPK, but it is a good example of how stocks go up after uplisting.



With the Dow hovering back around 11,000 it is getting increasingly difficult to find attractive value stock opportunities. However, by focusing on potential uplisting opportunities it is still possible to find stocks with the potential to double with a relatively low degree of risk.

The most difficult part of playing uplistings is judging the timing of the uplist. In the case of Sinocoking, the stock came public on Feb. 5 and with seemingly no advance notice uplisted on Feb. 18, only two weeks later. In other cases, such as Puda and Agritech, the companies leave many clues to the impending uplist including filing various 8Ks notifying investors about the appointment of the required independent directors or in some cases even announcing that they intend to or expect to uplist in the near future. And yet on the day they uplisted they still saw a double-digit jump in the share price.

In the case of Sinocoking, the stock ran from $12 pre-uplist to $18 in 2 days, and subsequently ran as high as $53.70 within a few short weeks. In the case of Puda and Agritech, both jumped by around 20% on the day their uplisting was announced even though it was widely known that the uplisting was coming. Puda uplisted at around $5 and now trades at over $11. China Agritech uplisted at a split-adjusted price of $6 and now trades at $23, having reached a high over $30.

In short, for each of these stocks getting in at the pre-uplist price provided a triple-digit return in a short period of time and for holding a stock that was clearly trading on a very low multiple, with minimal downside risk vs. the fundamentals.

If uplisting is such a profitable, low-risk strategy then how does it continue to persist? Why aren't all hot potential uplist companies bid up to fair value well in advance of the uplisting? The reason is that many institutional investors are specifically prohibited by their charters from investing in OTC stocks. In addition, many institutions have guidelines about minimum share prices and won't invest in low-priced stocks. As soon as the uplist happens, the institutional money flows in driving both price and volume to fair market levels.

As for the next uplisting opportunities, I am currently focused on New Energy Systems and Biostar Pharmaceuticals, both of which I see uplisting in the near future.

New Energy Systems has already announced that it intends to uplist in 2010 and currently meets the Nasdaq requirements for share price by a healthy margin. The company still needs to establish its corporate governance structures to satisfy Nasdaq but this is a very straightforward process and can happen very quickly. As this happens, NEWN will release a series of 8Ks notifying investors that they have established several board committees (audit, compensation and nominations) with a majority of independent directors. The only reason to take these corporate actions is to prepare for an uplisting. As a result, this type of announcement sends a clear signal to the market and has been known to cause share prices to jump in anticipation of the uplisting.

A good recent example is China JoJo Drugstores (CJJD.OB), which released several of these types of 8K filings and ran from $2.62 to as high as $5.00 on no other news over the period of about one week. So clearly investors are starting to figure out when an uplisting is becoming imminent. In the case of NEWN, they have already said that they are in the process of appointing independent board members and establishing the required committees so I chose to buy the stock before the 8Ks come out.

As for the timing of the 8Ks and the eventual uplisting, that is anyone's guess, it could be as short as a few weeks or as long as a few months. But after doing a significant amount of analysis, it is a stock I am comfortable to hold onto for a while, confident that it will be worth the wait in the same way that Puda and Agritech were.

NEWN released full year guidance of $1.23 per share for 2010, which is only 6.5 times earnings, whereas its Nasdaq comparables (such as Advanced Battery Technologies Incorporated (ABAT_) and Hong Kong Highpower Technology(HPJ_)) trade on P/E multiples in the mid-teens. So even if the stock shows some volatility I am unconcerned because it is still significantly undervalued.

In December 2009 Biostar Pharmaceuticals established all of the necessary corporate governance structures in exact accordance with Nasdaq specifications, so now it only needs to have its closing bid price stabilize above $4 for a set number of days and then it will meet all requirements for a Nasdaq listing. As a result, this is one that could happen very fast and with no notice. However, ultimately the timing on the uplisting depends on the formal Nasdaq approval, so while I always try to get in early, I also make sure I am prepared to wait a bit. Since I missed out on Sinocoking this way, I chose to buy Biostar early and not risk missing it.

Biostar has issued guidance of $18-20 million in net income which results in a forward P/E ratio of approximately 5-6x at current prices in the low $4 range. This low multiple is despite the fact that the company grew revenues and net income by 57% in 2009, and expects to nearly double them in 2010. Comparable Nasdaq companies (such as SVAC) trade at 2-3 times this multiple, so again it is a stock I am comfortable holding onto as I wait for the uplisting. (Note: in a previous article I had mistakenly noted the projected EPS of Biostar as $1.80, which is incorrect. As shown above, full year guidance is $18-20 million in net income.)
 

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I will give a personal example of how uplisting can help a stock.

A friend of mine who is far from a stock guru gave me a great tip on a stock to buy 10 or 12 months ago in MITK at 1 per share.
I did not listen to him because like I said, he is no stock market expert. But the term every blind squirrel finds an acorn every once in a while applies to this case.

He told me to buy at 1 6 or 8 months ago. 4 or 5 months later the stock got uplisted to the the NASDAQ and it now trades at over 12 a share 6 or 8 months later.

I even started a thread about this at this forum about that very stock.
I still hate myself for not getting in on that stock.

OPK could be the next big mover.

And we all got in at the ground floor thanks to following the insiders lead.
The insiders knew about this a long time ago.
And we took advantage by following along.

The NYSE has strict requirements to stay on the exchange, so OPK would not have wasted the time to get uplisted if they did not think the stock would do what it takes to stay there.

Here is the link to the thread my friend told me about the stock that uplisted and went through the roof.
http://www.therxforum.com/showthread.php?t=845325
 

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i remember that post about when to take a friends advice on a tip and i can imagine how it burns...i took a tip from a friend on PWRD about 3 months ago and go ahead and see where that led me...

i appreciate the explanation and write up... im in for a larger part of my portfolio then i should be but i am a believer even before this news...looking forward to the ride...
 

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$4.51 on the final day of trading on the AMEX
Lets see how it goes on the 1st day of the NYSE tomorrow.
This could be fun.
 

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ding ding ding
we are on the big board trading at $4.58
 

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Another great day with the market down over 100 points
4.67 now
 

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