Oregon Ducks: Bralon Addison... torn ACL 4 months ago.
Although they are talking about a potential return, it is likely that Addison will not be playing for a while and definitely will take him a while to get back in to top form.
So the Ducks lose their top two receivers (Huff as a senior) and Addison who had over 800 yards. They also lost their most dynamic player to the draft in Thomas and their star left tackle to injury.
That's a lot of pieces to lose, but Oregon is known for a factory of speed. Going to be interesting to see who fills these roles. They still have Mariotta and Marshall so regardless they are going to be competitive, but I would guess they will lose couple games this year.