Having spent a great deal of time in Panama over the years, as usual it can be a good/bad situation.
The Good is that you are dealing with one of the most modern settings in the region, with plenty of new infrastructure because of the impact of the banking industries (over 130 international banks have a presence right now). Hotels are excellent (The Bristol a personal favorite if you want something on the quiet side), Restaurants are quite good (Shula's Steakhouse likely to become the favorite of the off-shore crowd), there are some decent casinos (Cesar Park and Hotel Panama being the best, and there are plenty of places to bet live Race/Sports), and Punta Paitilla and Marbella are among the best neighborhoods to reside in all of Latin America.
The Bad is that it appears that there is only one Master License granted, forcing everyone under an umbrella, which is not a very good "control" situation at all. Very little leverage on dealing with tax or employment issues. The way that the license was issued has already created political enemies internally, especially among those that are already in the gaming industry in that country (CIRSA, Thunderbird and others have spent significant development $$$ through the years and were passed over). The government itself lacks stability, and the economy has been in a significant downturn the past two years. Related to that is the fact that extradition treaties between Panama and the U.S. are not favorable at all for this industry, and we strongly suggest any U.S. citizens doing their homework before making the move.
Except for a short "dry season" from December into March, the weather is swelteringly humid, all day every day. Brutal afternoon thunderstorms the rest of the year, and it can feel like living in a car wash.
As for the women, perhaps the most important indicator is that the overwhelming majority of the dancers in the clubs are either Colombian or Dominican.
Anyone that has been in San Jose for very long will likely enjoy the quality of life much more in Panama, except for the weather. But from an operations standpoint, those planning to move there should already plan on having their back-up location on standy.
Just some food for thought.