Hawai'i Rainbow Warriors (-3, 57) at UNLV Rebels, 4 p.m. ET
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Hale: Wait, did we say Tulane was the best 1-8 team in America? Upon further review, UNLV is the best 1-8 team in America. But they're both really terrific 1-8 teams. The Rebels are coming off their first win and have had a lead in the second half five times this season (they are just 1-4 in those games). The point is, UNLV is making progress under second-year coach Marcus Arroyo. Hawai'i, meanwhile, rarely embraces its role as favorite. The Rainbow Warriors are just 5-22-1 against the spread as a favorite since 2015. The road mark is even worse. Hawai'i has lost seven of its last nine road games and is just 1-4 ATS away from home in 2021. Plus, a 4 p.m. Eastern kickoff is essentially the same as asking Hawai'i to kick off at 9 a.m. on a Tuesday.
Pick: UNLV +3
No. 11 Texas A&M Aggies (-2.5, 55.5) at No. 15 Ole Miss Rebels, 7 p.m. ET on ESPN
Hale: It might be easy to look at Texas A&M's recent scoring totals -- 41 vs. Alabama, 35 vs. Missouri, 44 against South Carolina -- and assume Jimbo Fisher has worked out the kinks in the Aggies' offense. Perhaps. But in that 41-point outburst against the Tide, A&M finished with 379 total yards. It wasn't all that much better against Missouri (431) or the Gamecocks (477), and last week produced another mediocre performance against Auburn (409 yards, 20 points). The 477 yards against the Gamecocks represents a season high for A&M vs. a Power 5 opponent, while Ole Miss has finished with fewer than 464 just once (291 against Alabama). Of the Aggies' 15 touchdowns scored from the Alabama game through Auburn, three came via special teams or defense, and three more came after A&M got the ball in its opponent's territory.
Ole Miss has a massive advantage at QB, and while the Rebels' offense has felt a bit off the past few games, they've also held three of their last four opponents to 26 points or fewer. A&M needs big plays to score and has thrown for more than 200 yards just once against a Power 5 opponent. That's a good matchup for the Ole Miss D. Oddly, this is also just the second true road game of the season for A&M (which played Colorado in Denver and Arkansas in Dallas); the first was against lowly Missouri. FPI says the Rebels should be favored by 1.5, so we're happy to take the points here.
Pick: Ole Miss +2.5
Arizona State Sun Devils (-5.5, 44) at Washington Huskies, 7 p.m. ET
Connelly: Arizona State overcame three turnovers to handle USC comfortably last week. The Sun Devils outgained the Trojans by 2.6 yards per play and probably should have won by a lot more than 15. Now they face a UW team that has plenty of reasons to just about pack it in. Head coach Jimmy Lake has been suspended for a game, and offensive coordinator John Donovan, who probably should have never been hired, was fired on Sunday as well. The Huskies need to win two of three to reach bowl eligibility, and they do have "we've got nothing to lose" potential, but barring turnovers and/or a miraculous offensive performance (from a team that hasn't topped 24 points since September), ASU's advantage should be greater than 5.5 points.
Pick: Arizona State -5.5
No. 9 Notre Dame Fighting Irish (-5.5, 64) at Virginia Cavaliers, 7:30 p.m. ET
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ESPN Chalk home
Fortenbaugh: The state slogan may be "Virginia is for lovers," but this Saturday night in Charlottesville I'm switching that to "Virginia is for overs." After all, the Cavaliers fit the bill, ranking 11th in scoring and 102nd in scoring defense. Virginia has been involved in some exhilarating shootouts this season, with 115 total points being scored in the BYU game, 98 points produced in the North Carolina showdown, 88 points totaled in the Georgia Tech matchup and 67 points accumulated in the Louisville contest. I'm sure Brian Kelly and Notre Dame will be happy to oblige with an offense that has scored a healthy average of 35 points per game since being held to just 13 points against Cincinnati back on Oct. 2.
Pick: Over 64
Kansas Jayhawks at Texas Longhorns (-30.5, 61.5), 7:30 p.m. ET on ESPNU
Fulghum: You know the deal by now; fade Kansas football. Outside of its strangely competitive game against Oklahoma a few weeks ago, Kansas has been consistently getting waxed by the competition. The Jayhawks are 1-8 ATS this season and have a -249 point differential this season. Steve Sarkisian & Co. should run it up at will Saturday night in Austin.
Pick: Texas -30.5
Colorado Buffaloes at UCLA Bruins (-16.5, 57), 9 p.m. ET
Kezirian: Colorado has found an offense, scoring a combined 66 points in its last two games. It actually makes sense. Most teams evolve throughout the season, and that is particularly applicable with a freshman quarterback. Additionally, the Buffs are surrendering tons of points and thus find themselves facing relaxed defenses or even reserves in garbage time. Enter UCLA, which ranks in the bottom half of the country in various defensive statistics. The Bruins have lost back-to-back games but also have USC on deck, so I can envision an apathetic effort. All in all, I think we see enough points to cash the over.
Pick: Over 57
Nevada Wolf Pack at No. 22 San Diego State Aztecs (-2, 45.5), 10:30 p.m. ET
Fortenbaugh: San Diego State at any price cheaper than -3 is worth a play because Nevada should have lost to San Jose State last week. The Wolf Pack closed as a 12.5-point favorite and won by just three points despite being outgained by 82 total yards. Had Nevada lost that game like it should have, this price would be Aztecs -3.5 or greater, in my opinion. Styles make fights, and in this fight SDSU has a big edge in two key departments. First, the Aztecs love to run the ball, which will be problematic in the trenches for a Nevada program that ranks 79th in the country in opponent yards per rushing attempt (5.4). Second, Nevada's strength is its passing attack (third in the NCAA), which should be limited by an Aztecs defense that ranks fourth in the nation in opponent yards per passing attempt (5.4). Throw in SDSU's significant edge on special teams and I'm happy to lay two points in this spot.
Pick: San Diego State -2