I absolutly dont understand why people take a qb #1 overall. or even really high in the 1st round for that matter. I guess it depends some on your scoring system as well but you have to take a RB. Personally, i'd take foster but rice and mccoy are fine too. the dropoff from elite RB to decent RB is alot more then the dropoff from elite QB to decent qb. In my leagues scoring system mark sanchez finished last year as the #10 qb. And he may not even have been drafted. I took Stafford in like round 11 and he finished #3 qb. value can be had later with qb's. and its almost easy to get a pretty good qb, especially in a 10 team league. Ill freely admit that there will be some random Rb drafted in round 11 or so that will put up big numbers this year, but its alot easier to find a qb who will be pretty good.
Lets say you go QB in the 1st and RB at pick #24. ok, your way you take the #1 qb and likely the #14ish RB. if you go Rb in the 1st and qb in the 2nd you take the #1 RB and probably the #4 QB. the point differencial between the #1 and #4 qb is minimal. the point differencial between the #1 RB and #14 Rb is huge.