I'm obviously an ND fan, but I have watched every minute of their games this year and seen all of their home games and a few away games in person so I know the team pretty well.
They usually play very well in the first half in these big games. If I were to bet, I'd take ND 1H and UConn 2h and the game. If you remember in the big games (against ranked teams) this year at halftime they have been: up 6 @Pitt at half, down 1 vs. UConn, up 12 @Providence, down 2 @WV, up 3 vs. Marquette, down 3 @Louisville, up 18 vs Louisville, up 11 vs. Gtown, down 7 @Syracuse. The only real aberration is being down 16 @UCLA, where ND forgot to get off the plane.
The Irish will typically cover (often straight up) for 35 minutes and then blow up at the end as they just jack up 3s.